Yes, you can. You need a SpreadsheetWeb server license. Contact our sales team to purchase one.
You need to setup a Windows Virtual Machine on AWS. We recommend a c5.xlarge or equivalent. Note that you may need a higher configuration if you have complex workbook calculations or expect large number of concurrent users in your applications.
We also have Amazon Machine Images (AMI) with SpreadsheetWeb Server pre-installed available on AWS. Please contact your account executive to request access to our AMIs.